National Institute of Health research grant
Biological systems experience a wide variety of mechanical forces. Some are chronic and ubiquitous, such as gravity, while others are acute and localized, such as compression. It remains unclear which proteins transduce these mechanical forces. I build devices to apply altered gravity and compression to developing zebrafish and Drosophila, and investigate proteomic changes using Difference Gel Electrophoresis. Understanding mechanotransduction can help develop new treatments for diseases with mechanical aspects, such as age-related diseases and space travel.
For Carnegie Mellon University
Type Research grant